By Trish Greenhalgh, Professor of Primary Care Health Sciences, University of Oxford, Jose-Luis Jimenez, Distinguished Professor, Chemistry, University of Colorado Boulder, Shelly Miller, Professor of Mechanical Engineering, University of Colorado Boulder and Zhe Peng, Research Scientist, University of Colorado Boulder
Two years into the pandemic, most of us are fed up. COVID case rates are higher than they’ve ever been and hospitalisation rates are once again rising rapidly in many countries.
Against this bleak picture, we yearn to get back to normal. We’d like to meet friends in a pub or have them over for dinner. We’d like our struggling business to thrive like it did before the pandemic. We’d like our children to return to their once-familiar routine of in-person schooling and after-school activities. We’d like to ride on a bus, sing in a choir, get back to the gym, or dance in a nightclub without fear of catching COVID.
Which of these activities is safe? And how safe exactly? These were the questions we sought to answer in our latest research.
SARS-CoV-2, the virus that causes COVID, spreads mainly by airborne transmission. So, the key to preventing transmission is to understand how airborne particles behave, which requires knowledge from physics and chemistry.
Air is a fluid made up of invisible, rapidly and randomly moving molecules, so airborne particles disperse over time indoors, such as in a room or on a bus. An infected person may exhale particles containing the virus, and the closer you are to them, the more likely you are to inhale some virus-containing particles. But the longer the period you both spend in the room, the more spread out the virus will become. If you are outdoors, the space is almost infinite, so the virus doesn’t build up in the same way. However, someone can still transmit the virus if you’re close to them.
Viral particles can be emitted every time an infected person breathes, but especially if their breathing is deep such as when exercising or involves vocalisation such as speaking or singing. While wearing a well-fitting mask reduces transmission because the mask blocks the release of virus, the unmasked infected person who sits quietly in a corner is much less likely to infect you than one who approaches you and starts a heated argument.
All variants of SARS-CoV-2 are equally airborne, but the chance of catching COVID depends on the transmissibility or contagiousness of the variant (delta was more contagious than previous variants, but omicron is more contagious still) and on how many people are currently infected (the prevalence of the disease). At the time of writing, more than 97% of COVID infections in the UK are omicron and one person in 15 is currently infected (prevalence 6.7%). While omicron appears more transmissible, it also seems to produce less severe illness, especially in vaccinated people.
Likelihood of becoming infected
In our study, we have quantified how the different influences on transmission change your risk of getting sick: viral factors (transmissibility/prevalence), people factors (masked/unmasked, exercising/sitting, vocalising/quiet) and air-quality factors (indoors/outdoors, big room/small room, crowded/uncrowded, ventilated/unventilated).
We did this by carefully studying empirical data on how many people became infected in super spreader events where key parameters, such as the room size, room occupancy and ventilation levels, were well-documented and by representing how transmission happens with a mathematical model.
A sure-fire way to catch COVID is to be present in the red spaces. For example:
- Gather together with lots of people in an enclosed space with poor air quality, such as an under-ventilated gym, nightclub or school classroom
- Do something strenuous or rowdy such as exercising, singing or shouting
- Leave off your masks
- Stay there for a long time
To avoid catching COVID, try keeping in the green or amber spaces:
- If you must meet other people, do so outdoors or in a space that’s well-ventilated or meet in a space where the ventilation is good and air quality is known
- Keep the number of people to a minimum
- Spend the minimum possible amount of time together
- Don’t shout, sing or do heavy exercise
- Wear high-quality, well-fitting masks from the time you enter the building to the time you leave.
The actual risk will depend on the specific parameters, such as exactly how many people are in a room of what size. If you fancy putting in your own data for a particular setting and activity, you can try our COVID-19 Aerosol Transmission Estimator.
This article was originally published on GAVI on January 14, 2022
